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Malignant degeneration of long-standing fistula is extremely rare and only one case has been reported so far in 2005. We herein report the 2 nd case of longstanding entercutaneous fistula following left nephrectomy. The clinical pictures, radiological features are highlighted excision of the fistulous tract was done, which turned out to be squamous cell carcinoma. This case brings to notice that due to its insidious course, longstanding colo cutaneous fistula should be carefully examined for tumour development.
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